Endocrine Abstracts

Background: Thyroid cancer is the most frequent endocrine malignancy, with >7000 cases diagnosed in central Europe every year. Recently, ALK/EML4 translocations have been reported in single cases in anaplastic thyroid cancer (ATC). Little is known about the frequency of ALK alterations in poorly differentiated thyroid cancer (PTC). Our aim was to investigate the frequency of ALK alterations in patients with advanced thyroid carcinomas.Material and me...